Ontogenesis of human S-100 protein subunit positive histiocytes and lymphocytes

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Ontogeny of S-100 protein-positive histiocytes and lymphocytes in the human fetal lymphoreticular system.

In the human lymphoreticular system, the alpha and beta subunits of S-100 protein are found in ordinary monocyte-macrophages and non-phagocytic histiocytes such as Langerhans cells and interdigitating reticulum cells, respectively. The beta subunit is also present in some CD8+ T cells. In the present study, we investigated the ontogeny of these histiocytes and lymphocytes in humans. Yolk sacs a...

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S-100 beta positive human T lymphocytes: their characteristics and behavior under normal and pathologic conditions.

The characteristics of human S-100 beta-positive T lymphocytes (S-100 beta+ T cells) and their fluctuation in peripheral blood under normal and various pathologic conditions were investigated. S-100 beta+ T cells were small lymphocytes with no particular subcellular structures and showed a proliferative response to mitogens. They were present mainly in peripheral blood under normal conditions b...

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S S 100 Calcium - Binding Protein ▶ S 100 Proteins S 100 Proteins

S100 proteins were first discovered in 1965 by Moore as a major protein fraction (0.6% of total soluble protein) isolated from bovine brain (Moore 1965). The protein was given the name S100 due to its high solubility in saturated ammonium sulfate. Later experiments showed the S100 protein fraction constituted two different dimeric species comprised of two b protomers (S100B) or an a, b heterodi...

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S 100 P ( S 100 calcium binding protein P )

S100P protein consists of 95 amino acids with a molecular weight of 10.4 kDa. S100P is a Ca binding protein that belongs to S100 family ("Soluble in 100% saturated solution with ammonium sulfate") which was first isolated from human placenta and is therefore designated as "P". S100 family includes at least 26 members, which are thought to be expressed only in vertebrates and are present in a ti...

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Immunohistochemical studies of S-100 protein during postnatal ontogenesis of the brain of two strains of rats.

We have studied the dynamics of the appearance of cells reacting positively with anti-S-100 protein antiserum, during postnatal neurocytogenesis in the brain of rats of two strains differing in their susceptibility to sound stimuli. The postnatal time of appearance of cells reacting positively with anti-S-100 protein antiserum was somewhat later in rats susceptible to sound-induced seizures tha...

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ژورنال

عنوان ژورنال: Okayama Igakkai Zasshi (Journal of Okayama Medical Association)

سال: 1988

ISSN: 0030-1558,1882-4528

DOI: 10.4044/joma1947.100.5-6_441